Iggy antibody selector quickly search hundreds of thousands of antibodies available for purchase from vwr by selecting common antibody. Roundabout homolog 2 is a protein that in humans is encoded by the robo2 gene. We design and produce custom monoclonal antibodies tailored for your specific needs. Specific protocols boster provides comprehensive technical information for wb, ihcificc, flow cytometry sample preparation protocols, assay protocols, troubleshooting tips and assay optimization tips. This target gene encodes the protein roundabout guidance receptor 2 in humans. In questa sezione, cerchiamo di aiutarvi a trovare tutte le risorse da scaricare, link. Our first job is to listen to and observe what our customers need, and meet those needs with quality products and. Diseases associated with robo2 include vesicoureteral reflux 2, and vesicoureteral reflux. Defects in this gene are the cause of vesicoureteral reflux type 2. Robo1 and robo2 are two human homologs of the drosophila protein roundabout 24.
Recombinant antihuman angptl6 antibody creative biolabs. The data collected includes not only links to publications in pubmed, but also provides information about sample types, species, and experimental conditions. Driver robot is what can be considered a driver manager for all types of drivers. Robo and robo2 play distinct roles in midline guidance. Tlr2 is a member of the tolllike receptor tlr family and is expressed primarily by per.
Mouse monoclonal antibody raised against recombinant myd88. Western blot analysis of extracts from 293t cells, mock transfected or transfected with human rxr. The best feature yet of driver robot is how connected it is to the. Our boster quality guarantee for antikchip3 antibody covers its use in the following applications. View human robo2 antibody mab3147 validated in human. The recommended dilution ratiosconcentrations are for reference only and optimal. Robo1 is present on axons of all three tracts, robo2 is present in the l tract. Your home for breaking and local news, sports news and weather news in and around columbia and jefferson city. Rat anti mouse ly6ae antibody, clone d7 recognizes members of the lymphocyte activation protein6 ly6 multigene family. Antirobo2 antibodies are offered by a number of suppliers.
Hek293t cells transfected with either rc209001 overexpress plasmid red or empty vector control plasmid blue were immunostained by antipsmb9 antibody abin2455596, and then analyzed by. Robo2 belongs to the robo family, part of the immunoglobulin superfamily proteins that are highly conserved from fly to human. Robo2 roundabout guidance receptor 2 is a protein coding gene. We found an unexpectedly high frequency of robo2 missense variants in our cohort of patients. Purified antimouse p2x7r antibody p2x7r, also known as p2x7 receptor, belongs to the family of ligandgated ion channel receptors.
This target gene encodes the protein cxc motif chemokine receptor 2 in humans and may also be known as il8ra, cd182, cdw128b, cmkar2, il8r2, cxc chemokine receptor type 2, and cxcr2. Antikar2 yeast antibodies monoclonal antibody democracy. Rxralpha retinoid x receptor alpha, nr2b1 antibody can be used in western blotting. A chromosomal aberration involving robo2 is a cause of multiple congenital abnormalities, including severe bilateral vur with ureterovesical junction defects. Among its related pathways are signaling by robo receptor and development slitrobo signaling. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. The glycosylation pathway is required for the secretion of slit and for. Immunoglobulins igs are produced by b lymphocytes and secreted into plasma. Antirsk2 mouse rsk2 antibody product cell applications. Your top supplier for voltagegated potassium channel research. Recombinant antihuman robo4 antibody creative biolabs is committed to providing highly customized comprehensive solutions with the best quality to advance our global clients projects. The software can do it all when it comes to drivers including monitoring them, backing them up, and installing them.
Moreover, we showed that missense changes in robo2 are associated not only with. Diseases associated with robo2 include vesicoureteral reflux 2 and familial vesicoureteral reflux. Click on a disease name to see all genes associated with that disease. This target gene encodes the protein roundabout guidance receptor 1 in humans and may also be known as dux. Monoclonal antibody for studying robo2 in the neuroscience research area. Immunohistochemistry analysis of paraffinembedded human breast carcinoma tissue, using zscan22 antibody a14735. Antikchip2 antibody from alomone labs is a highly specific rabbit polyclonal ab directed against an epitope of the human protein. Moreover, we showed that missense changes in robo2 are associated not only with vurcakut phenotype but also with familial vur. Antibodies antimouse gr1 antibody, clone rb68c5, apc for a complete list of antibodies, including other conjugates, sizes and clones, as well as related products available from stemcell technologies.
Sandwich elisa was conducted by using rc6a as the capture antibody and rc6b as the detection antibody. Gene ontology go annotations related to this gene include identical protein binding and axon guidance receptor activity. Human robo2 is a 175 kda member of the roboroundabout receptor family and is a 57 amino acid aa type i transmembrane tm protein. Robo2 is a receptor for slit2, molecules known to function in axon guidance and cell migration. If you cannot find antibodies you need from the above list, please dont hesitate to contact us for a free consultation. It contains an extracellular domain ecd comprised of five. This article on a gene on human chromosome 3 is a stub.
Or freely design a custom antibody development project not covered by abinsure program. Incubate membrane and primary antibody at the appropriate dilution and diluent as recommended in the product datasheet in 10 ml primary antibody dilution buffer with gentle. Atcc stands ready to support our customers needs during the coronavirus pandemic. Robo2 roundabout guidance receptor 2 gene gtr ncbi. Anticxcr2 antibody products anticxcr2 antibodies are offered by a number of suppliers. View human robo2 antibody af3147 validated in human. Apr 15, 2020 a chromosomal aberration involving robo2 is a cause of multiple congenital abnormalities, including severe bilateral vur with ureterovesical junction defects. This target gene encodes the protein roundabout guidance receptor 1 in humans and may also be known as dux, dutt1, sax3, roundabout homolog 1, and deleted in u twenty twenty. Alternatively spliced transcript variants encoding different isoforms have been described for robo2. This translocation disrupts robo2 and produces dominantnegative robo2 proteins that abrogate slitrobo signaling in vitro.
The ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kda that. In questa sezione, cerchiamo di aiutarvi a trovare tutte le risorse da scaricare, link correlati e documentazione di aiuto che consentono di collegare il telefono cellulare, telefono android o tablet al pc e configurare in modo corretto. Robo2 is a receptor for slit2, molecules known to function in axon. Weve preset your country and language selections based on your location. Robo2 roundabout, axon guidance receptor, homolog 2 drosophila is a proteincoding gene. Antirobo1 antibody products antirobo1 antibodies are offered by a number of suppliers. Diseases associated with robo2 include vesicoureteral reflux. Specific protocols boster provides comprehensive technical information for wb.
The protein expression data from 44 normal human tissue types is derived from antibody based protein profiling using immunohistochemistry. Recombinant antihuman angptl6 antibody creative biolabs is committed to providing highly customized comprehensive solutions with the best quality to advance our global clients projects. The data collected includes not only links to publications in. Go annotations related to this gene include identical protein binding and axon guidance receptor activity. Recombinant antihuman robo4 antibody creative biolabs. Anticalsenilincsenkcnip3 antibody pa2272 bosterbio. Tissue expression of robo2 summary the human protein atlas. This antibody reacts with bovine, canine, equine, guinea pig, human, mouse, rabbit, rat, zebrafish samples.
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